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目的观察后程超分割适形治疗食管癌的治疗反应及近期疗效。方法37例食管癌患者均经过食管点片及胃镜证实,均为鳞癌,并为首程病例。采用常规放疗及后程超分割适形治疗相结合。15MV-X线,前4周,分割剂量为200cGy/次,1次/d,5次/周,后2周140cGy/次,2次/d,照射剂量参考线为90%等剂量曲线。结果进食改善率81.08%(30/37),近期有效率为100%(37/37),急性放射性食管炎发生率为51.33%(19/37),放疗后食管并发症发生率为48.65%(18/37),主要为食管狭窄、溃疡,未出现穿孔及大出血等。结论后程超分割适形治疗食管癌在临床中应用是可行的,值得推广。
Objective To observe the therapeutic response and short-term curative effect of late-stage hyperfractionated conformal treatment of esophageal cancer. Methods 37 cases of esophageal cancer patients were confirmed by esophageal dot and gastroscopy, are squamous cell carcinoma, and the first case. The use of conventional radiotherapy and subsequent hyper-conformal treatment combined. 15MV-X, the first 4 weeks, the dose of 200cGy / times, once / d, 5 times / week, 2 weeks after 140cGy / times, 2 times / d, radiation dose reference line for the 90% isodose curve. Results The improvement rate of eating was 81.08% (30/37), the effective rate was 100% (37/37), the incidence of acute radiation esophagitis was 51.33% (19/37), and the incidence of esophageal complications after radiotherapy was 48.65% 18/37), mainly esophageal stenosis, ulcers, no perforation and bleeding and so on. Conclusions Post-procedure hyperfractionation conformal treatment of esophageal cancer in the clinical application is feasible, it is worth promoting.