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患者,男,29岁。因脑外伤后癫痫服癫健安治疗(400mg,3次/日)已1年,初控制良好,无明显不适。近2个月来发作频度增加,自己加用苯妥英钠0.1,3次/日,合并用药第三天起渐有四肢和口唇“发抖”,至1周时上述症状加重,以致影响生活,于1982年6月28日入院。体检见四肢(上肢重)有运动性和姿势性震颤,两手向前平伸时可见大幅度的扑翼样震颤,无眼震,肌张力、感觉和反射系统无明显异常。角膜K-F环(-),无蜘蛛痣,肝脾不大,肝功能及血氨正常。在严密观察下,先停用苯妥英钠并将癫健安量加至600mg,3次/日,震颤在3天内完全消失;继用苯妥英钠0.1,3次/日,而癫健安减至
Patient, male, 29 years old. Epilepsy due to epilepsy after epilepsy health treatment (400mg, 3 times / day) has been 1 year, early control of good, no obvious discomfort. In the past two months, the frequency of seizures increased by 0.1,3 times per day with phenytoin plus one day. The third day after the combination therapy, the limbs and lips “trembled” gradually. By the first week, the above symptoms were aggravated, affecting life June 28, 1982 admission. Physical examination showed limbs (upper extremities weight) have movement and postural tremor, both hands forward flat stretch can be seen when a substantial flapping-wing tremor, no nystagmus, muscle tone, sensory and reflex system was not abnormal. Corneal K-F ring (-), no spider nevus, hepatosplenomegaly, liver function and normal blood ammonia. Close observation, the first to stop using phenytoin and epilepsy amount to 600mg, 3 times / day, tremor completely disappeared within 3 days; following the use of phenytoin 0.1,3 times / day, and epilepsy reduced to