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目的研究同型半胱氨酸(Hcy)的测定在急性冠脉综合征(ACS)中的临床意义。方法 100例诊断为急性冠脉综合征住院治疗的患者为研究组,另选取同期保健科健康人群100例作为对照组,两组研究对象均完成对Hcy的检测,分析比较Hcy变化水平。结果研究组患者Hcy明显高于对照组,差异有统计学意义(P<0.05);线性回归分析显示,Hcy和急性冠脉综合征的发病具有正相关性(r=0.883,P<0.05)。结论急性冠脉综合征患者的Hcy与正常健康人群相比较高,临床对Hcy水平的检测可作为疾病预后和治疗的指标。
Objective To investigate the clinical significance of homocysteine (Hcy) in acute coronary syndrome (ACS). Methods A total of 100 hospitalized patients with acute coronary syndrome were selected as the study group. Another 100 healthy subjects in the health department of the same period were selected as the control group. Hcy was measured in both groups, and Hcy level was analyzed. Results The Hcy in the study group was significantly higher than that in the control group (P <0.05). The linear regression analysis showed that there was a positive correlation between Hcy and the incidence of acute coronary syndrome (r = 0.883, P <0.05). Conclusions Hcy in patients with acute coronary syndrome is higher than that in normal healthy people. The detection of Hcy in clinic can be used as an index of disease prognosis and treatment.