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作者对14名经活检证实的不同病期和不同活动程度的结节病患者和8名正常人的周围血液和支气管肺泡灌洗液中的淋巴细胞,应用直接免疫荧光单克隆抗体(Leula,Leu3a,Leu2a)分析T淋巴细胞总数(Leu1a),抑制细胞毒素T细胞(即Tsc,Leu2a~+)或辅助诱导T淋巴细胞(Thi,Leu3a~+)的分布恃况。他们未能发现患者周围血液中T淋巴细胞亚群有何变化,但支气管肺泡炎灌洗液中的Tsc细胞的比例大大超过正常人(患者为36.0%SD±17.6%,正常15%SD±5.6%
The authors of 14 biopsied sodomysis at different stages and different degrees of activity in patients with sarcoidosis and 8 normal peripheral blood and bronchoalveolar lavage fluid lymphocytes using direct immunofluorescence monoclonal antibody (Leu, Leu3a , Leu2a) to analyze the distribution of T lymphocytes (Leu1a) and cytotoxic T cells (Leu2a ~ +) or T lymphocytes (Thi, Leu3a ~ +). They failed to detect any change in T lymphocyte subsets in the peripheral blood of patients, but the proportion of Tsc-cells in bronchoalveolar-lavage fluid was significantly higher than in normal subjects (36.0% SD ± 17.6%, 15% SD ± 5.6% %