抗菌药物的合理使用和细菌耐药问题已经成为全球严重的公共卫生问题之一。抗菌药物的滥用将导致细菌耐药性增长以及由此而产生的难治性院内感染，药源性死亡增加，导致医疗质量下降，医疗费用增长[1]。为规范抗菌药物的合理应用，我院运用质量管理工具——戴明循环：计划(Plan)、执行(Do)、检查(Check)、改进(Action)循环(简称PDCA循环) [2]，对抗菌药物的临床应用实施干预，并持续跟踪监控，以达到持续改进的目的。 The rational use of antibacterials and the issue of bacterial resistance have become one of the most serious public health problems in the world. Abuse of antimicrobial drugs will lead to increased bacterial resistance and the resulting intractable nosocomial infections, leading to increased drug-induced deaths, resulting in a decline in the quality of care and an increase in medical costs [1]. In order to standardize the rational application of antimicrobial agents, we use quality management tools - Deming Cycle: Plan, Do, Check, and PDCA cycle [2] The clinical application of antibacterials is intervened and monitored continuously to achieve continuous improvement.