库欣病是指垂体促肾上腺皮质激素(ACTH)依赖性的库欣综合征类型,也是最常见的库欣综合征的临床类型。一旦明确库欣病的诊断,经蝶窦手术是首选治疗方法。手术目标是完全切除肿瘤,纠正高皮质醇状态,同时尽量保存垂体功能。本文就库欣病的术前诊断及围手术期激素替代治疗进行综述。 Cushing’s disease refers to the type of ACTH-dependent Cushing’s syndrome and is also the most common clinical form of Cushing’s syndrome. Once the diagnosis of Cushing’s disease is clear, transsphenoidal surgery is the preferred treatment. The goal of surgery is complete resection of the tumor, correction of high cortisol status, and preservation of pituitary function as much as possible. This article reviews Cushing’s disease preoperative diagnosis and perioperative hormone replacement therapy.