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目的探讨左甲状腺素钠治疗老年甲状腺功能减退综合征的临床效果及安全性。方法 60例老年甲状腺功能减退综合征患者,随机分为对照组和实验组,各30例。对照组患者采用甲状腺片进行治疗,实验组采用左甲状腺素钠进行治疗,对比两组患者的临床疗效和不良反应的发生情况。结果经过2个月的治疗后,实验组患者总有效率(86.67%)高于对照组(63.33%),且不良反应发生率(6.67%)明显低于对照组(16.67%),差异具有统计学意义(P<0.05)。结论左甲状腺素钠治疗老年甲状腺功能减退综合征具有显著的临床疗效,且不良反应发生率较低,临床可推广应用。
Objective To investigate the clinical efficacy and safety of levothyroxine in the treatment of senile hypothyroidism syndrome. Methods Sixty elderly patients with hypothyroidism were randomly divided into control group and experimental group, with 30 cases in each group. Patients in the control group were treated with thyroid tablets. The experimental group was treated with levothyroxine, and the clinical efficacy and adverse reactions of the two groups were compared. Results After 2 months of treatment, the total effective rate (86.67%) in the experimental group was significantly higher than that in the control group (63.33%), and the incidence of adverse reactions (6.67%) was significantly lower than that of the control group (16.67%) Significance (P <0.05). Conclusion Levothyroxine treatment of elderly hypothyroidism syndrome has a significant clinical effect, and the incidence of adverse reactions is low, the clinical application can be promoted.