对51例消化道间叶性肿瘤进行临床、病理及治疗分析。分析表明,消化道间叶性肿瘤约占消化道肿瘤的3.4％,男女比例2.2:1,平均年龄49.03岁,常见部位有胃(45.09％)、食管(23.53％)及回盲部、结肠(13.73％);常见组织学类型是平滑肌瘤(39.21％)、恶性淋巴瘤(29.41％)及平滑肌肉瘤(1.60％);手术切除是唯一有效的治疗手段。其预后较胃癌佳,5年生存率在50％以上。 Clinical, pathological, and therapeutic analysis of 51 patients with gastrointestinal mesenchymal tumors were performed. The analysis showed that gastrointestinal mesenchymal tumors accounted for 3.4% of digestive tract tumors, the ratio of male to female was 2.2:1, and the average age was 49.03 years. Common sites included stomach (45.09%), esophagus (23.53%), ileocecal junction, and colon ( 13.73%); common histological types are leiomyoma (39.21%), malignant lymphoma (29.41%), and leiomyosarcoma (1.60%); surgical resection is the only effective treatment. The prognosis is better than that of gastric cancer. The 5-year survival rate is above 50%.