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目的探讨腹腔镜卵巢囊肿剥除术中不同止血方法对卵巢功能的影响。方法将80例单侧良性卵巢囊肿行腹腔镜卵巢囊肿剥除术的患者随机分为观察组和对照组,每组各40例。观察组术中采用缝合止血法,对照组术中采用传统的双极电凝止血法。观察两组患者术前、术后3月、6月的雌二醇(Estradiol,E2)、促卵泡激素(follicle-stimulating hormone,FSH)、促黄体生成素(luteinizing hormone,LH)、孕酮(progestcrone,P)水平,术后月经变化及妊娠率。结果观察组患者术后3个月各激素水平与术前比较,差异无统计学意义(P>0.05);对照组患者E2下降,LH、FSH升高,与术前比较差异有统计学意义(P<0.05);术后6个月,两组激素水平与术前比较差异无统计学意义(P>0.05),观察组月经改变率和妊娠率明显优于对照组(P<0.05)。结论腹腔镜下卵巢囊肿剥除术中创面电凝止血会引起卵巢功能的损害,而采用缝合止血可更好的保留卵巢功能,有利于保留患者生育功能,值得临床推广应用。
Objective To investigate the effect of different hemostasis methods on ovarian function in laparoscopic ovarian cyst excision. Methods Eighty patients with unilateral benign ovarian cysts undergoing laparoscopic ovarian cyst excision were randomly divided into observation group and control group, 40 cases in each group. Observation group intraoperative suture hemostasis, control group intraoperative use of traditional bipolar coagulation hemostasis. The levels of estradiol (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH), progesterone progestcrone, P) levels, postoperative menstrual changes and pregnancy rates. Results The levels of hormones in the observation group at 3 months after operation were not significantly different from those before operation (P> 0.05). E2 in the control group decreased and the levels of LH and FSH increased (P <0.05) (P <0.05). There was no significant difference in hormone levels between the two groups at 6 months after operation (P> 0.05). The rate of change of menstruation and the pregnancy rate in the observation group were significantly better than those in the control group (P <0.05). Conclusion Laparoscopic surgery in ovarian cyst excision wound hemostasis will cause damage to ovarian function, and the use of suture hemostasis can better retain ovarian function is conducive to preserving the patient’s reproductive function, it is worthy of clinical application.