硝酸甘油是一种具有悠久历史的抗心绞痛药物,由于它的疗效确切,至今仍不失为治疗心绞痛的首选药物。当心绞痛发作时,舌下给药(一般为0.5mg),能迅速缓解疼痛。临床上多用于心绞痛急性发作或心绞痛患者在活动前含用起预防作用。但在临床上也有将硝酸甘油口服(每日三次,每次0.5mg),作心绞痛常规预防药,长期服用,这是不妥当的。一般在连续服用数天后,即可产生耐药。2～3周后耐药达高峰。这时虽然加大剂量也可奏效,但有形成高铁血红蛋白的可能,使红细胞失去带氧功能,造成心肌再度缺氧,这对心绞痛患者是很不利的。因此,我们认为用硝酸甘油口服给药作心绞痛病人常规 Nitroglycerin is a long history of anti-anginal drugs, because of its exact effect, is still the treatment of angina preferred drug. When angina attacks, sublingual administration (usually 0.5mg), can quickly relieve pain. Clinically used for angina pectoris or angina pectoris before use in patients with preventive activities. However, there are also clinically oral nitroglycerin (three times a day, each 0.5mg) for routine preventive angina medicine, long-term use, which is not appropriate. Generally take a few days in a row, you can produce resistance. 2 to 3 weeks after the peak drug resistance. Although this time can increase the dose can be effective, but the possibility of formation of methemoglobin, red blood cells lose oxygen function, resulting in myocardial hypoxia again, which angina patients is very unfavorable. Therefore, we believe that oral administration of nitroglycerin for angina patients routine