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目的:分析精液中处理前前向运动精子总数(TPMSC)与处理后前向运动精子总数(PTMSC)的相关性。方法:收集426对不孕夫妇共563个IUI周期的临床资料,统计分析TPMSC与正常形态精子百分率、精子浓度、活力、PTMSC的相关性,按照TPMSC不同分成3个区间组:<10×106组(A组)、(10~19)×106组(B组)、≥20×106组(C组),比较这3组的前向运动精子(PMS)回收率和周期临床妊娠率。结果:TPMSC与正常形态精子百分率、精子浓度、活力、PTMSC有显著相关性(P<0.001);不同TPMSC数量组处理后PMS回收率无统计学差异(P>0.05);周期临床妊娠率分别为6.82%、17.59%、16.35%,A组周期妊娠率明显低于B组、C组(P<0.05),B、C组间差异无统计学意义(P>0.05)。结论:TPMSC是反映精液质量的重要综合参数,是夫精人工授精选择和评估预后的重要参考指标。
OBJECTIVE: To analyze the correlation between total sperm motility (TPMSC) and total motile sperm motility (PTMSC) after treatment in semen. Methods: The clinical data of 563 IUI cycles from 426 pairs of infertile couples were collected. The correlation between TPMSC and the percentage of normal spermatozoa, sperm concentration, vitality and PTMSC was statistically analyzed. According to the difference of TPMSC, there were 3 interval groups: <10 × 106 (Group A), (10 ~ 19) × 106 group (group B) and ≥20 × 106 group (group C). The recovery rate of forward motile sperm (PMS) and the rate of clinical pregnancy were compared between the three groups. Results: There was a significant correlation between TPMSC and the percentage of normal spermatozoa, sperm concentration, vitality and PTMSC (P <0.001). There was no significant difference in PMS recoveries between groups with different TPMSC numbers (P> 0.05). The clinical pregnancy rates were 6.82%, 17.59%, 16.35%. The pregnancy rate in group A was significantly lower than that in group B and C (P <0.05). There was no significant difference between group B and C (P> 0.05). Conclusion: TPMSC is an important comprehensive parameter that reflects the quality of semen and it is an important reference index for the selection of artificial insemination and prognosis evaluation.