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目的:观察不同方案的抗菌药物防治急性阑尾炎围手术感染的经济效果的差别。方法:90例行阑尾切除术的患者随机分为3姐,头孢哌酮／舒巴坦(1:1)联合甲硝唑组(Cefp组),头孢曲松钠联合甲硝唑组(Cefq组),左氧氟沙星联合甲硝唑组(Leof组)均在手术前30 min给药,术后连续2 d用药。采用药物经济学最小成本进行分析。结果:3组患者的疗效均无统计学差异。成本最低的为左氧氟沙星联合甲硝唑组。结论:左氧氟沙星联合甲硝唑是这3种方案中最佳的防治方案。
OBJECTIVE: To observe the difference in the economic effects of different programs of antimicrobial agents in the prevention and treatment of perioperative infections of acute appendicitis. Methods: Ninety patients undergoing appendectomy were randomly divided into 3 groups: Cefp group (cefp group), cefoperazone / sulbactam group (1: 1) and metronidazole group ), Levofloxacin plus metronidazole group (Leof group) were administered 30 min prior to surgery and were administered for 2 consecutive days. Use the lowest cost of pharmacoeconomics for analysis. Results: There was no significant difference in the efficacy between the three groups. The lowest cost of levofloxacin combined metronidazole group. Conclusion: Levofloxacin combined with metronidazole is the best of these three programs to prevent and control.