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目前认为N端-B型利钠肽前体(NT-pro BNP)主要通过尿排泄。尿NT-pro BNP测量的临床意义尚不甚明了。方法及结果观察94例慢性心力衰竭(CHF)病人(年龄58±11岁,男性79%)和20例年龄、性别相配的健康对照者,分别以125I-iothalomate消除和131I-hippuran反映肾小球滤过率和有效肾血浆
It is currently believed that N-terminal-B type natriuretic peptide precursor (NT-pro BNP) is mainly excreted through the urine. The clinical significance of urine NT-pro BNP measurement is not yet clear. Methods and Results 94 patients with chronic heart failure (CHF) aged 58 ± 11 years (79%) and 20 age-matched healthy controls were enrolled in this study. 125I-iothalomate elimination and 131I-hippuran were used to detect glomeruli Filtration rate and effective renal plasma