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目的评价~(99m)Tc-HYNIC-TOC生长抑素受体显像诊断和鉴别诊断胰岛素瘤的临床价值。方法回顾性分析近11年来65例胰岛素瘤患者的~(99m)Tc-HYNIC-TOC显像结果 ,并与胰腺灌注CT、B超或内镜超声结果比较。结果 65例患者均进行~(99m)Tc-HYNIC-TOC显像,阳性28例,检出率43.1%。部分患者进行胰腺灌注CT、B超或内镜超声检查,检出率分别为92.5%、25.6%和76.9%。结论单独应用~(99m)Tc-HYNIC-TOC显像对胰岛素瘤的定性诊断和鉴别诊断临床价值有限,需联合应用多项分子影像诊断技术。
Objective To evaluate the clinical value of ~ (99m) Tc-HYNIC-TOC somatostatin receptor imaging in the diagnosis and differential diagnosis of insulinoma. Methods We retrospectively analyzed the results of ~ (99m) Tc-HYNIC-TOC imaging in 65 patients with insulinoma over the past 11 years and compared them with CT, B ultrasound or endoscopic ultrasonography. Results All the 65 patients were diagnosed by ~ (99m) Tc-HYNIC-TOC, and the positive rate was 28 (43.1%). Some patients with pancreatic perfusion CT, B ultrasound or endoscopic ultrasonography, the detection rates were 92.5%, 25.6% and 76.9%. Conclusion The clinical value of ~ (99m) Tc-HYNIC-TOC imaging in the diagnosis and differential diagnosis of insulinoma is limited, and a number of molecular imaging diagnostic techniques should be used in combination.