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颅内细胞移植为脑卒中后遗症的治疗开辟了一条崭新的道路。目前可供颅内细胞移植的细胞供体有:神经干细胞或神经前体细胞、永生化细胞系、骨髓基质细胞等。移植的方法包括:病灶同侧半球内移植、病灶对侧半球内移植、脑室内移植以及经静脉和颈动脉途径移植。移植时间、位点、移植细胞的剂量和免疫因素等多方面的因素影响移植的疗效。
Intracranial cell transplantation has opened up a whole new path for the treatment of stroke sequelae. Currently available for intracranial cell transplantation of cell donors are: neural stem cells or neural progenitor cells, immortalized cell lines, bone marrow stromal cells. Transplantation methods include: ipsilateral hemispheric transplantation within the lesion, transfusions within the contralateral hemisphere, intraventricular and intraventricular and carotid artery transplants. Transplant time, site, dose of transplanted cells and immune factors and other factors affect the efficacy of transplantation.