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目的寻找一条切实可行针对女性生殖器疱疹的治疗方案。方法对我区565例确诊为生殖器疱疹的女性患者,随机分为A.B.C.D四组。A组采用阿昔洛韦片间歇疗法(疱疹发作时连续服药一周)治疗;B采用泛昔洛韦片间歇疗法(疱疹发作时连续服药一周)治疗;C组采用伐昔洛韦片间歇疗法(疱疹发作时连续服药一周)治疗;D组采用万乃洛韦间歇疗法(疱疹发作时连续服药一周)治疗。结果经过一年持续治疗,停药后观察一年,A组152例,总有效率达51.97%,B组132例,总有效率达85.60%,C组142例,总有效率达83.80%,D组139例,总有效率达59.71%。经统计学处理,B组和C组的治疗效果比较显著。结论根据女性生殖器疱疹的发病特点,经研究观察,泛昔洛韦在治疗上疗效显著,且安全性较高、经济实惠,值得在临床推广使用。
Objective To find a feasible treatment for female genital herpes. Methods 565 female patients diagnosed as genital herpes in our district were randomly divided into A.B.C.D four groups. Group A was treated with acyclovir intermittent therapy (continuous treatment for one week during herpes episodes); B was treated with famciclovir intermittent therapy (continuous treatment for one week during herpes episodes); group C was treated with intermittent regimens of valacyclovir (herpes episodes Continuous medication for a week) treatment; D group with valacyclovir intermittent therapy (herpes attack continuous medication for a week) treatment. Results After a year of continuous treatment, observed after a year of withdrawal, group A 152 cases, the total effective rate was 51.97%, 132 cases in group B, the total effective rate was 85.60%, 142 cases in group C, the total effective rate was 83.80% Group D 139 cases, the total effective rate 59.71%. After statistical analysis, B group and C group treatment effect is more significant. Conclusions According to the characteristics of female genital herpes, famciclovir has significant curative effect in treatment, which is safe, economical and worthy of clinical application.