目的比较腹腔镜与开腹手术治疗结肠癌的临床疗效及术后初期生活质量差异。方法选择我院2008年3月—2011年2月治疗的结肠癌患者79例,其中腹腔镜组42例,开腹组37例,比较两组的术中情况和术后1周、4周时的生活质量。结果腹腔镜组在术中出血量、术后肠功能恢复时间、术后下床活动时间、恢复工作时间、住院总天数等方面优于开腹组,而手术时间长于开腹组、总住院费方面略高于开腹组,差异均有统计学意义(P<0.05);腹腔镜组患者术后1周疼痛情况优于开腹组,差异有统计学意义(P<0.05);而术后生活质量测定核心量表(QLQ-C30)其他领域评分比较,差异均无统计学意义(P>0.05)。结论腹腔镜结肠癌根治术具有创伤小、恢复快,术后初期疼痛轻等优点,值得临床推广应用。 Objective To compare the clinical efficacy of laparoscopic and laparotomy in the treatment of colon cancer and the difference of initial postoperative quality of life. Methods A total of 79 patients with colon cancer who were treated in our hospital from March 2008 to February 2011 were selected. Among them, 42 cases were laparoscopic and 37 cases were laparotomy. The intraoperative results and postoperative 1 week and 4 weeks The quality of life Results The laparoscopic group was superior to the open group in terms of blood loss, postoperative intestinal function recovery time, postoperative ambulation time, recovery working time and the total number of days of hospitalization, while the operation time was longer than that of the laparotomy group. The total hospitalization cost (P <0.05). The pain in laparoscopic group at 1 week after operation was better than that in open group (P <0.05), while the difference was statistically significant There was no significant difference in scores of QLQ-C30 in other fields (P> 0.05). Conclusions Laparoscopic radical mastectomy has the advantages of less trauma, quick recovery and early postoperative pain, which is worthy of clinical application.