本文首次报道沙石粉碎厂工人细胞遗传学监测结果。研究对象为印度一沙石粉碎厂50名男性工人(经分析所接触沙石中主要成分为SiO_2,占50～60％),以25名年龄配对未接触过沙石的教师作对照,实验组平均年龄30.92岁,对照组平均年龄30.36岁。根据吸烟和饮酒习惯将实验组及对照组进一步分类,每日吸烟多于10支、平均饮酒200ml者定为吸烟和饮酒。分别采集2组实验对象的静脉血(内加肝素防凝),取血样2ml,加入4ml含20％胎牛血清、0.1ml植物血细胞凝集素和 This paper reports for the first time the results of cytogenetic monitoring of workers in gravel mill. The study was conducted on 50 male workers at a gravel crushing plant in India (50-60% of the sand in the gravel contacted by the analysis) and 25 age-matched teachers without gravel. The experimental group The average age of 30.92 years old, control group average age of 30.36 years. According to smoking and drinking habits, the experimental group and the control group were further classified. More than 10 cigarettes were smoked per day, and the average drinking volume of 200ml was defined as smoking and drinking. Blood samples were collected from 2 groups of venous blood (anticoagulant plus heparin), 2ml of blood sample, 4ml of 20% fetal bovine serum, 0.1ml of phytohemagglutinin and