婴儿细菌性结膜炎的抗菌药物筛选

来源 :儿科药学杂志 | 被引量 : 0次 | 上传用户:okhere
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通过对235例婴儿细菌性结膜炎的病原菌及药敏试验,采用妥布霉素、庆大霉素、氧氟沙星眼液分组对照治疗观察.结果表明三种药物的总药敏度分别是89.39%、39.39%和65.66%(P<0.005),临床总有效率分别为92.00%、54.00%和72.00%(P<0.005),总药敏度与临度与临床总有效率基本一致.妥布霉素不仅广谱且抗菌作用最强,还对绿脓杆菌作用突出,其眼液也适用于婴儿. Through the pathogenic bacteria and drug susceptibility test of 235 cases of infant bacterial conjunctivitis, tobramycin, gentamicin and ofloxacin ophthalmic solution were used to control the treatment.The results showed that the total drug sensitivity of the three drugs were The overall clinical effective rates were 92.3%, 89.39%, 39.39% and 65.66% respectively (P <0.005). The total clinical effective rates were 92.00%, 54.00% and 72.00%, respectively Not only broad-spectrum and antibacterial effect of clothomycin strongest, but also the role of Pseudomonas aeruginosa prominent, its ophthalmic also applies to infants.
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