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目的分析重度黄疸型病毒性肝炎患者行腺苷蛋氨酸联合丹参注射液治疗的效果。方法 66例重度黄疸型病毒性肝炎患者,按照治疗方案不同分成对照组和观察组,各33例。对照组患者行苦黄注射液治疗,观察组患者行腺苷蛋氨酸联合丹参注射液治疗。比较两组疗效和血清学指标。结果治疗后,观察组总有效率为96.97%,高于对照组的78.79%,差异具有统计学意义(P<0.05);观察组患者碱性磷酸酶、谷草转氨酶、直接胆红素水平分别为(60.70±10.30)U/L、(50.21±8.10)U/L、(18.20±3.09)μmol/L,均低于对照组的(98.52±15.40)U/L、(68.25±10.18)U/L、(28.68±4.50)μmol/L,差异具有统计学意义(P<0.05)。结论重度黄疸型病毒性肝炎患者行腺苷蛋氨酸联合丹参注射液治疗能够改善其临床症状,且优化血清学指标,具有较高应用价值。
Objective To analyze the effect of adenosine methionine combined with Salvia miltiorrhiza injection in patients with severe icterohepatitis. Methods Sixty-six patients with severe jaundice-type viral hepatitis were divided into control group and observation group according to different treatment regimen, and each group had 33 cases. Patients in the control group were treated with Kuhuang injection, and patients in the observation group were treated with adenosine methionine combined with Salvia miltiorrhiza injections. The curative effect and serological index of two groups were compared. Results After treatment, the total effective rate in the observation group was 96.97%, which was higher than that in the control group (78.79%), the difference was statistically significant (P <0.05); the levels of alkaline phosphatase, aspartate aminotransferase and direct bilirubin in observation group were (60.70 ± 10.30) U / L, (50.21 ± 8.10) U / L and (18.20 ± 3.09) μmol / L, respectively, which were lower than those in the control group (98.52 ± 15.40) U / L , (28.68 ± 4.50) μmol / L, the difference was statistically significant (P <0.05). Conclusions The treatment of patients with severe jaundice virus hepatitis with adenosine methionine combined with Salvia miltiorrhiza injection can improve its clinical symptoms and optimize the serological markers, which is of high value.