目的探讨数字钼靶三维引导下钩针定位乳腺微钙化灶切除活检的价值。方法收集杭州市第一人民医院2011年4月—2013年4月采用数字钼靶三维引导下钩针定位切除活检的94例微钙化病例进行分析。结果患者均为女性,钼靶提示存在单侧微钙化灶不伴肿块影及结构紊乱,平均年龄42.8岁,左侧45例,右侧49例。发现非典型增生3例,乳腺癌11例(11.7%),导管原位癌5例,浸润性导管癌6例,其中ⅠA 3例,ⅡA 2例,ⅡB1例。术后2例腔内感染病例,无活动性出血病例。结论通过钼靶三维引导下钩针定位乳腺微钙化灶切除活检可以发现早期乳腺癌,操作安全。从而能够早期诊断、早期治疗,改善患者预后。 Objective To investigate the value of digital mammography guided three-dimensional crocheting needle biopsy in breast microcalcification. Methods Ninety-four patients with microcalcifications undergoing needle biopsy under the guidance of three-dimensional digital mammography were collected from April 2011 to April 2013 in Hangzhou First People's Hospital. Results The patients were all female. Molybdenum target suggested unilateral microcalcification without mass shadow and structural disorder. The mean age was 42.8 years old, 45 on the left and 49 on the right. Three cases of atypical hyperplasia, 11 cases of breast cancer (11.7%), 5 cases of ductal carcinoma in situ and 6 cases of invasive ductal carcinoma were found, including 3 cases of IA, 2 cases of IIA and 1 case of IIB. Postoperative 2 cases of intracavitary infection, no cases of active bleeding. Conclusion The mammography guided three-dimensional positioning of the breast microcalcification cesarean section biopsy can detect early breast cancer, safe operation. So that early diagnosis, early treatment, improve patient prognosis.