论文部分内容阅读
目的探讨千金子醋糊外用对豚鼠体癣模型的影响。方法采用须癣毛癣菌接种于豚鼠皮肤创面制作体癣模型,观察千金子醋糊大、小剂量组(0.2 5,0.15 g·m L-1)外用对体癣模型豚鼠体癣症状积分、病灶皮肤逆培养、病灶局部病理变化的影响。结果大、小剂量千金子醋糊外用可显著降低体癣模型豚鼠的体癣症状积分(P<0.0 1,P<0.0 5);明显提高病灶皮肤逆培养转阴率(P<0.0 5);显著改善体癣病灶局部病理变化(P<0.0 1)。结论千金子醋糊外用对豚鼠体癣模型有较好的治疗作用。
Objective To investigate the effect of Qianjinzi vinegar on the model of tinea corporis in guinea pigs. Methods Trichophyton mentagrophytes were inoculated on guinea pig skin wounds to make tinea corporis models. The effects of Qianjin vinegar paste large and small dose group (0.2 5,0.15 g · m L -1) Inverse skin culture of lesions, the pathological changes of lesions. Results Large and small doses of gold vinegar for external application could significantly reduce the body ringworm symptom scores (P <0.0 1, P <0.0 5) of guinea pigs with tinea corporis; significantly reduce the negative rate of reverse skin culture (P <0.05); Significantly improved the local pathological changes of tinea pedis (P <0.0 1). Conclusion Qianjinzi vinegar external use on guinea pigs tinea pedis model has a better therapeutic effect.