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目的 :探析多普勒超声心动图(DE)估测肺动脉高压(PAH)血流动力学参数的临床意义。方法 :前瞻性分析2013年2月~2016年3月在我院接受住院治疗的99例经DE筛查确诊为PAH的患者的临床资料。比较不同肺动脉压力(PAP)及不同病因者DE与右心导管术(RHC)估测的血流动力学参数值,并分析DE与RHC测值间的相关性。结果 :所有病因中(除慢性阻塞性肺病COPD外),同一疾病组中分别用RHC和DE法检测到的PAH患者无显著差异。RHC确诊的PAH患者(86例)估测的PASP、m PAP、m RAP值与DE估测的值呈显著相关性。PAP中度上升者RHC与DE呈显著高度相关性,而重度上升者则呈中度相关,轻度上升者两者的相关度最低。结论 :DE与RHC在PAH者血流动力学参数值的估测中具有显著的相关性,但在不同PAP分级及不同病因者中有明显差异。
Objective: To investigate the clinical significance of using Doppler echocardiography (DE) to evaluate the hemodynamic parameters of pulmonary hypertension (PAH). Methods: The clinical data of 99 patients who were diagnosed as PAH by DE screening from February 2013 to March 2016 in our hospital were prospectively analyzed. The pulmonary artery pressure (PAP) and the hemodynamic parameters of different etiologies of DE and right heart catheterization (RHC) were compared, and the correlation between DE and RHC was analyzed. RESULTS: There was no significant difference in PAH among all causes (except COPD except chronic obstructive pulmonary disease) and RHC and DE in the same disease group. The PASP, m PAP, m RAP values estimated by RHC-confirmed PAH patients (86 patients) were significantly correlated with DE estimates. PAP moderately elevated RHC and DE was highly correlated, while those with severe ascenders were moderately correlated, mildly associated with the lowest correlation between the two. Conclusion: DE and RHC have significant correlations in the estimation of hemodynamic parameters in patients with PAH, but there are significant differences between them in different PAP grades and in different etiologies.