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黄连素(小檗碱,Berberine)为黄连等植物中的主要有效成份,属异喹啉生物碱,临床上主要用于抗菌、抗病毒、抗原虫等,近年来发现其在治疗某些心血管疾病时疗效显著,现概述如下。 1.治疗心律失常 黄连素已用于治疗各种类型的心律失常。有人等应用黄连素治疗快速型心律失常41例,其中室性早搏19例,房性早搏8例,阵发性室上性心动过速6例,阵发性房颤5例,慢性房颤3例,均采用口服黄连素0.4g,每日4次,显效后继续用5日,再逐渐减量维持,疗程2～4周。结果显效15例,有效13例,显效率36.6％,总有效率68.3％。应用
Berberine (berberine) is a major active ingredient in plants such as berberine, belonging to isoquinoline alkaloids. It is mainly used for antibacterial, antiviral, antiprotozoal, etc. in clinical practice. It has been found to treat certain cardiovascular diseases in recent years. The efficacy of the disease is significant, as outlined below. 1. Treatment of arrhythmia Berberine has been used to treat various types of arrhythmias. Some people used berberine in the treatment of 41 cases of tachyarrhythmias, including 19 cases of premature ventricular contractions, 8 cases of atrial premature beats, paroxysmal supraventricular tachycardia in 6 cases, paroxysmal atrial fibrillation in 5 cases, chronic atrial fibrillation 3 Cases were all treated with oral berberine 0.4g, 4 times a day, 5 days after being markedly effective, and then gradually reduced and maintained for 2 to 4 weeks. The results were markedly effective in 15 cases, effective in 13 cases, significant efficiency 36.6%, and total effective rate 68.3%. application