一、为什么还要继续寻找新的微生物代谢物? 如果我们看一眼市场上所提供的长长的——可以说是太长的——抗生素制剂目录单,不禁要问:还有什么必要继续寻找新的抗生素呢?目前市场上已有50多种青霉素和头孢菌素衍生物出售,还有30种已在临床试用。表一综合了目前在各领域使用抗生素的情 Why continue to look for new microbial metabolites? If we take a look at the long, long-term list of antibiotics available on the market, we can not help but ask: what else is needed to continue looking for New Antibiotics? More than 50 penicillins and cephalosporin derivatives have been marketed and 30 are in clinical trials. Table I combines the current use of antibiotics in various fields