尽管对缺血和再灌注引起小肠粘膜损伤的组织学变化形式已有较多研究,但针对这种损伤后的修复方式、时间过程和发生机制却注意甚少。新近Park和Haglund报告说,他们检查了规定缺血后不等时间的鼠小肠段的活组织标本,认为正常肠粘膜组织恢复所需时间随缺血时间的长短而定。缺血时间越长,粘膜损伤修复所需时间也越长。然而中等程度的缺血(即无血灌流45分钟)大多数动物的粘膜组织都能 Although histological changes of intestinal mucosal damage caused by ischemia and reperfusion have been studied more and more, little attention has been paid to the repair method, time course and mechanism of the injury. Recently, Park and Haglund reported that they examined biopsies of the small intestine of mice that dictate the duration of ischemia and concluded that the time required for recovery of normal intestinal mucosa depends on the length of the ischemic period. The longer the ischemia, the longer it takes to repair mucosal damage. However, moderate ischemia (ie, 45 minutes without hemoperfusion) mucosal tissue in most animals