本文介绍了设计剂型的一些基本知识。设计药物的剂型首先要考虑临床治疗的需要,其次要充分了解药物的性质和所设计剂型的稳定性。同时还应通过体外和体内试验了解药物的溶出速度和吸收、分布、排泄及代谢等情况,以便设计出病人乐于使用、生物利用度高、临床效果好的剂型。 This article describes some of the basics of designing dosage forms. The design of drug dosage forms must first consider the need for clinical treatment, and secondly, to fully understand the nature of the drug and the stability of the designed dosage form. Also in vitro and in vivo tests should understand the drug dissolution rate and absorption, distribution, excretion and metabolism, etc., in order to design a patient willing to use, high bioavailability, good clinical effect of the dosage form.