根据文献报告,氯霉素对一般的伤寒病有显著疗效,但对严重的病例往往不见奏效,有人认为甚至可使病情恶化。有些学者曾进行动物伤寒病的实验,结果发现经氯霉素治疗后,虽然热度下降,但动物仍不免死亡;并且观察到有臀上腺皮质功能减退的现象,因而建议用皮质酮治疗.在临床上,过去也曾有单独使用皮质酮治疗伤寒病的报告,结果虽亦有退热作用,但伤寒桿菌依然繁 According to the literature, chloramphenicol has a significant effect on the general typhoid fever, but often fails to work in severe cases, some people think even worsened. Some scholars have conducted experiments on animal typhoid fever and found that chloramphenicol treatment, although the heat decreased, but the animals still died; and the observed hypogastric dysfunction phenomenon, it is recommended corticosterone treatment. Clinically, in the past there have been reports of treatment of typhoid fever with corticosterone alone, although the results also have antipyretic effect, but still typhoid bacillus