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目的 探讨氟乙酰胺和毒鼠强中毒不能分辨时先用乙酰胺治疗的疗效。方法 对两种灭鼠药中毒不能分辨的 48例患儿先用特效解毒药乙酰胺治疗 ,每次肌注 0 1g/kg ,根据病情每日 2～ 4次。经毒物检测确诊后 ,37例氟乙酰胺中毒者继续用乙酰胺治疗 ,5～ 7天停药 ;11例毒鼠强中毒者停用乙酰胺。结果 37例氟乙酰胺中毒者仅有 1例因当地医院未能及时用乙酰胺 ,导致来我院时已发生严重呼吸衰竭和脑疝 ,经 10h抢救无效而死亡外 ,其余 36例均痊愈出院。 11例毒鼠强中毒者经先用乙酰胺治疗也无任何乙酰胺的毒副反应 ,均痊愈出院。结论 氟乙酰胺和毒鼠强两种灭鼠药中毒不能分辨时先用乙酰胺治疗效果满意 ,有较高的临床实用价值。
Objective To investigate the efficacy of acetamide treatment when fluoroacetamide and tetramine poisoning can not be distinguished. Methods 48 cases of children who can not distinguish two kinds of rodent poisoning were treated with special antidotes acetamide. Each time intramuscular injection of 0 1g / kg, according to the disease 2 to 4 times a day. 37 cases of fluoroacetamide poisoning continued to be treated with acetamide after 5 to 7 days of withdrawal after confirming the detection of toxic substances. Acetic acid was discontinued in 11 cases of tetramine poisoning. Results 37 cases of fluoroacetamide poisoning in only 1 case due to the local hospital failed to use acetamide, resulting in our hospital had severe respiratory failure and hernia, died after 10h and died, the remaining 36 patients were discharged . 11 cases of tetramine poisoning by acetamide treatment before any acetamide side effects, were cured and discharged. Conclusion Fluoroacetamide and tetramine two rodenticide poisoning can not be resolved when the first treatment with acetamide satisfactory results, a higher clinical value.