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目的探讨血粘度和凝血纤溶动态图在动脉粥样硬化性疾病中的变化及意义。方法采用ＦＡＳＣＯ－９４全自动粘度快测仪和凝血纤溶动态图仪对３８例动脉粥样硬化性疾病患者和３０例正常对照进行血粘度和凝血纤溶动态图的测定。结果血粘度指标中除血沉和血沉方程Ｋ值外，全血粘度、血浆粘度、红细胞压积、全血还原粘度、红细胞聚集指数、红细胞变形指数均显著性高于对照组（Ｐ<０．０３５～０．００１）；凝血纤溶动态图中的凝血指标凝固启动时间、１分钟凝固程度、最大凝固程度、到达最大凝固时间和纤溶指标平衡时间、１分钟纤溶程度、完全溶解时间、平均溶解程度较对照组有显著性差别（Ｐ< ０．０３６～０．００１）。结论动脉粥样硬化性疾病患者存在血液高凝状态和高粘血症，并且两者相互影响。
Objective To investigate the changes and clinical significance of blood viscosity and coagulation and fibrinolytic activity in atherosclerotic disease. Methods 38 cases of atherosclerotic disease and 30 normal controls were measured by FASCO-94 automatic viscosity detector and coagulation-fibrinolytic dynamic analyzer. Results Blood viscosity, plasma viscosity, hematocrit, whole blood reduced viscosity, erythrocyte aggregation index and erythrocyte deformability index were all significantly higher than those of the control group (P <0.035 ~ 0.001); coagulation and fibrinolytic activity of the coagulation index coagulation start time, 1 minute coagulation degree, the maximum degree of coagulation, to reach the maximum coagulation time and fibrinolysis equilibrium time, 1 minute fibrinolysis, complete dissolution time, average Solubility than the control group were significantly different (P <0.036 ~ 0.001). Conclusions Patients with atherosclerotic disease have blood hypercoagulability and hyperviscosity, and the two affect each other.