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1970～1980年以色列的8个医疗中心共收住急性非淋巴细胞白血病(ANLL)510例。由于尸检做得不多,对无症状者也未常规作腰穿,故本组中仅有13例(2.5％)诊断为临床中枢神经系统白血病(CNL)。其中女性8例,男性5例;年龄23～64岁。患者中急粒5例,急粒单5例,急单2例,未分化型1例。每1患者再跟按人种、性别、年龄及治疗方法与其相同的无CNL之ANLL病人2例(作为对照),进行配对研究。结果:诊断ANLL时的衰弱、背痛、关节痛、发热、脾肿大、淋巴结肿大、苍白、肝肿大与消瘦等症状、体征,在伴CNL组与无CNL组之间无明显区别,
Between 1970 and 1980, 510 Israeli acute leukemia (ANLL) patients were admitted to eight medical centers in Israel. Since autopsy did not do much, asymptomatic who did not routinely wear lumbar, so only 13 cases (2.5%) of this group diagnosed as clinical CNS. Including 8 females, 5 males; aged 23 to 64 years. In patients with acute pellet in 5 cases, acute pellet in 5 cases, urgent orders in 2 cases, undifferentiated in 1 case. Each patient was followed up with 2 matched ANLL patients without CNL by gender, age, and method of treatment (as controls) for a paired study. Results: There were no significant differences between CNL group and non-CNL group in diagnosing the symptoms and signs of ANLL such as weakness, back pain, joint pain, fever, splenomegaly, enlarged lymph nodes, pale, hepatomegaly and emaciation,