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[目的 ]观察血吸虫病患者治疗前后特异性IgG4抗体的变化。[方法 ]ELISA法。 [结果 ]2 7例血吸虫病患者治疗前SEA IgG4和AWA IgG4阳性率分别为 96 3%和 10 0 % ,平均OD值分别为 1 6 2和 0 72。治疗后 6月复查 18例 ,阳性率分别为 94 4%和 10 0 % ,平均OD值分别为 1 0 6和 0 5 6。治疗后 12月复查 2 7例 ,阳性率分别为 96 3%和 92 6 % ,平均OD值分别为 0 99和 0 5 8。 [结论 ]2 7例血吸虫病患者SEA IgG4和AWA IgG4治疗前后阳性率无明显变化 ,但抗体水平有所下降。
[Objective] To observe the changes of specific IgG4 antibody in patients with schistosomiasis before and after treatment. [Method] ELISA method. [Results] The positive rates of SEA IgG4 and AWA IgG4 in 27 cases of schistosomiasis patients before treatment were 96 3% and 100% respectively, with the average OD values of 1 62 and 0 72, respectively. After treatment, 18 cases were reviewed in June, the positive rates were 94.4% and 100% respectively. The average OD values were 106 and 0.56 respectively. Twenty-seven cases were retrospectively reviewed in December after the treatment. The positive rates were 96 3% and 92 6% respectively, with mean OD values of 0 99 and 0 58, respectively. [Conclusion] There was no significant change in the positive rate of SEA IgG4 and AWA IgG4 before and after treatment in 27 cases of schistosomiasis, but the antibody level decreased.