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对离体大鼠心脏用乏氧Ｋ一Ｈ液涨注１５ｍｉｎ后，再用正常Ｋ一Ｈ液复灌，可引发再灌注心律失常（ＲＡ），观察川芎嗪（ＴＭＰ．２０ｍｇ·Ｌ￣（－１））对ＲＡ的影响。结果发现用ＴＭＰ灌注后，ＲＡ发生率显著下降（Ｐ＜０．０１），持续时间也明显缩短，从而提示ＴＭＰ可有效地预防ＲＡ的发生。
Reperfusion arrhythmia (RA) was induced by reperfusion with normal K-H solution after 15 minutes of up-regulation of the isolated rat heart with hypoxia K-H solution. TMP was treated with 20 mg · L- 1)) on the impact of RA. The results showed that with TMP perfusion, the incidence of RA decreased significantly (P <0.01), the duration was significantly shortened, suggesting that TMP can effectively prevent the occurrence of RA.