细胞凋亡是细胞的主动性死亡过程 ,它在生物体的发育、自身稳定中起重要作用。病毒感染是常见的诱导细胞凋亡的因素 ,而作为打破宿主防御体系的一种策略 ,许多病毒自身的基因组编码有抗细胞凋亡的基因。本文综述了杆状病毒及其一些基因产物对细胞凋亡的诱导与抑制作用。 Apoptosis is the active cell death process, which plays an important role in the development of the organism and its own stability. Viral infection is a common cause of apoptosis, and as a strategy to break the host defense system, many of the virus’s own genomes encode anti-apoptotic genes. This article reviews the induction and inhibition of apoptosis by baculovirus and some of its gene products.