Unreinforced Masonry(URM) is the most common partitioning material in framed buildings in India and many other countries.Although it is well-known that under lateral loading the behavior and modes of failure of the frame buildings change significantly due to infill-frame interaction,the general design practice is to treat infills as nonstructural elements and their stiffness,strength and interaction with the frame is often ignored,primarily because of difficulties in simulation and lack of modeling guidelines in design codes.The Indian Standard,like many other national codes,does not provide explicit insight into the anticipated performance and associated vulnerability of infilled frames.This paper presents an analytical study on the seismic performance and fragility analysis of Indian code-designed RC frame buildings with and without URM infills.Infills are modeled as diagonal struts as per ASCE 41 guidelines and various modes of failure are considered.HAZUS methodology along with nonlinear static analysis is used to compare the seismic vulnerability of bare and infilled frames.The comparative study suggests that URM infills result in a significant increase in the seismic vulnerability of RC frames and their effect needs to be properly incorporated in design codes. Unreinforced Masonry (URM) is the most common partitioning material in framed buildings in India and many other countries. Though it is well-known that under lateral loading the behavior and modes of failure of the frame buildings change significantly due to infill-frame interaction, the general design practice is to treat infills as nonstructural elements and their stiffness, strength and interaction with the frame is often ignored, and because of difficulties in simulation and lack of modeling guidelines in design codes. The Indian Standard, like many other national codes, does not provide explicit insight into the anticipated performance and associated vulnerability of infilled frames. This paper presents an analytical study on the seismic performance and fragility analysis of Indian code-designed RC frames buildings with and without URM infills. Infills are modeled as diagonal struts as per ASCE 41 guidelines and various modes of failure are considered linear static analysis is used to compare the seismic vulnerability of bare and infilled frames. the comparative study suggests that a fracture of RC frames and their effect needs to be properly incorporated in design codes.