高血压的病因和发病机制复杂,目前尚不完全清楚。研究结果发现,血管内皮结构和功能的损伤参与了高血压的发生发展,与高血压的发病机制密切相关[1]。因此,对血管内皮损伤进行干预治疗,已成为防治高血压和预防远期心血管事件的重要环节,具有血管保护作用的血管紧张素转换酶抑制剂 The etiology and pathogenesis of hypertension are complicated and not yet fully understood. The results showed that vascular endothelial structure and function of the damage involved in the development of hypertension, closely related to the pathogenesis of hypertension [1]. Therefore, the intervention of vascular endothelial injury has become an important part of the prevention and treatment of hypertension and long-term cardiovascular events, with angiotensin-converting enzyme inhibitors