论文部分内容阅读
目的从血流速度、分支直径、T型分叉角度及血液黏度的血流动力学角度,并结合相关医学病例,研究T型分叉血管中血液流动对血栓形成的影响,从多学科角度分析并验证医学研究中的有关血栓形成机理的猜测。方法建立T-型动脉血管的几何模型,采用计算流体动力学方法对血管内流场进行数值分析研究,分析不同条件的流动对血栓形成影响。结果在分叉血管附近的支血管和主血管中分别形成了两处较大区域的涡流区域,另外,在分叉交接处的下游位置也出现了一处较小的区域,这些区域速度较低,剪应力出现突然增大趋势,符合血栓形成,因此成为“最适成栓位置”。结论血栓在“最适成栓位置”的形成还与分支血管直径、血管中血流速度、分叉角度以及血液黏度等有密切关系。
Objective To study the influence of blood flow in T-shaped bifurcation vessels on thrombus formation from the perspective of hemodynamics of blood flow velocity, branch diameter, T-bifurcation angle and blood viscosity in combination with related medical cases. From a multidisciplinary perspective And to validate speculation about the thrombosis mechanism in medical research. Methods The geometric model of T-shaped artery was established. The computational fluid dynamics method was used to analyze the internal flow field and analyze the influence of different conditions on thrombus formation. As a result, two large swirl areas were formed in the branch and main blood vessels near the bifurcation vessel, respectively. In addition, a small area appeared downstream of the bifurcation junction, and these areas were lower in speed , A sudden increase in shear stress trend, in line with thrombosis, it becomes “the most suitable embolization position ”. Conclusions The formation of thrombus in “the most suitable position for embolization ” is also closely related to the branch vessel diameter, blood flow velocity in blood vessels, bifurcation angle and blood viscosity.