在伴有大量蛋白尿的人类肾病和肾病动物模型中,足突融合是最主要和最常见的形态改变,同时也是一些疾病(如微小病变肾病)的特征性形态改变。因此,早在1957年就关注对足突融合形态结构和足突融合机制的研究。一方面,一些免疫因素、生化因子以及血流动力学改变参与足突融合过程,另 Foot process fusion is the most important and most common morphological change in animal models of human nephropathy and nephropathy with large amounts of proteinuria and is also a characteristic morphological change in some diseases such as minimal change nephropathy. Therefore, as early as 1957, attention was paid to the study of the fusion of foot processes and the process of foot fusion. On the one hand, some immune factors, biochemical factors and hemodynamic changes involved in foot process of fusion, and the other