目的分析婴幼儿轮状病毒(RV)感染致心肌损害的状况。方法对2007年6月至2009年9月桂林市人民医院64例腹泻患儿采用金标免疫法检测大便中RV抗原,根据检测结果 ,将其分为2组,即RV抗原阳性组(28例)与RV抗原阴性组(36例),比较两组治疗前、RV抗原阳性组治疗前后肌酸激酶同工酶(CK-MB)、肌酸激酶(CK)、乳酸脱氢酶(LDH)、天冬氨酸转移酶(AST)、体温、心率之间的差异。结果 (1)RV抗原阳性组CK-MB、LDH、AST、体温明显增高,心率明显增快。与RV抗原阴性组相比,RV抗原阳性组体温略高(P>0.05),CK-MB明显升高(P<0.01),心率明显加快(P<0.05)。(2)RV抗原阳性组治疗后CK、CK-MB、体温和心率均明显下降(P均<0.01)。(3)RV抗原阴性组CK-MB与体温、心率无相关性,体温与心率呈正相关;RV抗原阳性组CK-MB与体温、心率的相关系数分别为0.385(P<0.05)和0.587(P<0.01),具有明显相关性,但体温与心率无相关性。结论 RV阳性腹泻患儿CK-MB高,存在心肌损伤,且与心率呈正相关。 Objective To analyze the status of myocardial damage caused by rotavirus (RV) infection in infancy. Methods gold standard immunoassay stool antigen RV 64 cases of children with diarrhea in June 2007 to September 2009 Guilin People’s Hospital, according to test results, will be divided into two groups, namely RV antigen positive group (28 cases ) And RV antigen negative group (36 cases). Before treatment, the positive expression of CK-MB, CK, LDH, Aspartate aminotransferase (AST), body temperature, heart rate difference between. Results (1) CK-MB, LDH, AST in RV antigen-positive group were significantly increased, and heart rate was significantly increased. Compared with RV antigen negative group, RV antigen positive group was slightly higher body temperature (P> 0.05), CK-MB was significantly higher (P <0.01), heart rate was significantly faster (P <0.05). (2) CK, CK-MB, body temperature and heart rate of RV antigen-positive group were significantly decreased after treatment (all P <0.01). (3) RV antigen negative group CK-MB and body temperature, heart rate no correlation, body temperature and heart rate were positively correlated; the RV antigen expression CK-MB and body temperature, heart rate correlation coefficients were 0.385 (P <0.05) and 0.587 (P <0.01), with a significant correlation, but no correlation between body temperature and heart rate. Conclusion Children with RV-positive diarrhea have high CK-MB, myocardial damage, and a positive correlation with heart rate.