Coupled effects on a single point mooring (SPM) system subjected to the combined action of wind, waves and current are studied in this paper. Due to the complicatedness of the sea state and the huge size of the vessel, physical experimental study is both time consuming and uneconomical, whereas the numerical study is cost-effective and DNV software provides powerful SESAM software in solving the issues. This paper focuses on the modeling process of the SPM system, catenary equilibrium calculation, static analysis of the vessel in three different scenarios, and dynamic response simulation of the SPM system under environmental excitations. The three scenarios in study are as follows: the SPM is under the combined function of (a) wind, waves and current, (b) wind and waves, (c) current and waves. They are so set that one can compare the contributions of different types of loads in both static and dynamic studies. Numerical study shows that wind and current are the two major factors contributing to the mooring line tension, and surge and sway are the two dominant motions of the moored vessel subjected to environmental excitations.