无胃原发病变的食道腺癌很少见。Raphael在1312例食道癌中发现10例(0.8%),Turnbull和Goodner统计为45/1859例(2.4%),而食道上1/3腺癌自1900年以来总共只报告了20例。本文报告一例食道上段原发性腺癌。患者43岁,男性,1974年5月发现咽部疼痛,经间接喉镜,尿分析,血液化验,颈部软组织照象和喉部分泌物培养均为阴性。1974年9月出现吞咽困难,体重减轻,吞钡发现颈段食道有6cm长的不规则充盈缺损。食道镜见一溃疡性蕈状病变阻塞管腔。支气管镜检查发现食道肿瘤侵蚀气管后壁,活检诊断为低分化腺癌,来源于异位胃粘膜。由于肿瘤已不能切除,又未发现转移,故行4 Esophageal adenocarcinoma without primary gastric lesions is rare. Raphael found 10 cases (0.8%) in 1312 cases of esophageal cancer, 45/1859 cases (2.4%) in Turnbull and Goodner, and only a total of 20 cases of esophageal upper 1/3 adenocarcinoma have been reported since 1900. This article reports one case of primary adenocarcinoma of the upper esophagus. The patient, 43 years old, was male and was found to have pharyngeal pain in May 1974 and was negative by indirect laryngoscopy, urinalysis, blood tests, neck soft tissue imaging, and laryngeal secretion culture. In September 1974, dysphagia, weight loss, and swallowing found a 6 cm long irregular filling defect in the cervical esophagus. The esophagoscope showed an ulcerous verrucous lesion that blocked the lumen. Bronchoscopy revealed that the esophageal tumor eroded the posterior trachea and was biopsy-diagnosed as poorly differentiated adenocarcinoma, originating from the ectopic gastric mucosa. Since the tumor has not been removed and no metastasis has been found, line 4