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目的 了解酵母样真菌的感染特点和耐药情况。方法 真菌培养采用常规方法 ,用API2 0CAUX鉴定 ;药敏试验采用微量稀释法。结果 5 8例真菌中 ,念珠菌 48株 ,其中白念珠菌 2 6株 ,占 45 .6 1% ,其它酵母样菌 9株 ;重症监护病房、呼吸内科、神经内科、骨科所占比例高 ,均在 10 %以上 ;酵母样菌、白假丝酵母菌对酮康唑、咪康唑、氟康唑的敏感性高。结论 酵母样菌的检出率与病人基础疾病密切相关 ;白假丝酵母菌药敏结果和酵母样菌药敏综合结果有明显区别 ;对氟康唑等药物的敏感性有下降趋势
Objective To understand the infection characteristics and drug resistance of yeast-like fungi. Methods Fungus culture using conventional methods, with API2 0CAUX identification; susceptibility testing using micro-dilution method. Results Among the 58 cases of fungi, Candida albicans was 48, of which Candida albicans was 26 (45.61%) and other yeast-like strains (9). The intensive care unit, respiratory medicine, neurology and orthopedics occupied a high proportion, Are more than 10%; yeast-like bacteria, Candida albicans on ketoconazole, miconazole, fluconazole high sensitivity. Conclusion The detection rate of yeast-like bacteria is closely related to the patients’ underlying diseases. The sensitivity of Candida albicans is obviously different from that of yeast-like bacteria. The sensitivity to fluconazole and other drugs is declining