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目的分析40例丁胺卡那霉素与洁霉素联合应用治疗呼吸道感染引起死亡的相关因素。方法观察联合应用丁胺卡那霉素和洁霉素治疗呼吸道感染死亡40例,进行常规病理学检查及心血IgE测定。结果所有病例均有呼吸道炎症,常规尸检未发现心、脑、肾等重要脏器有明显疾患。镜下观察肺部及细支气管未见明显嗜酸性粒细胞增多等过敏反应特点。心血IgE测定均在正常范围。结论治疗呼吸道感染时首先应慎重应用丁胺卡那霉素与洁霉素。其次应注意用药方式和控制输液速度。
Objective To analyze the related factors of 40 cases of amikacin combined with lincomycin in the treatment of death caused by respiratory tract infection. Methods Forty patients with respiratory tract infection were treated with combination of amikacin and lincomycin, and routine pathological examination and blood-IgE determination were performed. Results All cases had respiratory inflammation, no obvious autopsy found heart, brain, kidney and other important organs have obvious diseases. Microscopic observation of the lungs and bronchioles showed no obvious eosinophilia and other allergic reactions. Inhalation of IgE in the normal range. Conclusion The first treatment of respiratory tract infection should be carefully applied to amikacin and lincomycin. Second, we should pay attention to medication and control infusion speed.