八珍汤对老龄大鼠血液流变学改善作用的研究

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以八珍汤10g/kg(八珍汤Ⅰ组)、20g/kg(八珍汤Ⅱ组)的剂量饲养18月龄大白鼠40天,同时分别投喂等容量的百年乐原液与蒸馏水作为阳性对照组与空白对照组。实验结果表明:八珍汤(Ⅱ组)和百年乐均可显著降低大白鼠的全血粘度(P<0.01)、血浆粘度(P<0.01)和纤维蛋白原含量(P<0.01),还能明显抑制大白鼠的血小板聚集作用,八珍汤(Ⅱ组)还能促进其血小板的解聚作用。结论:一定剂量的八珍汤对血液的“粘”、“浓”、“凝”、“聚”状态均具有明显的改善作用,初步为八珍汤的“活血化瘀”作用提供了实验依据。 Eighteen-month-old rats were fed with Bazhen Decoction 10g/kg (Bazhen Decoction I group) and 20g/kg (Bazhen Decoction II Decoction) for 40 days, and they were fed with the same volume of 100-year-old Le Centron and distilled water as positive respectively. Control group and blank control group. The experimental results show that Bazhen Decoction (Group II) and Breitlingen can significantly reduce the whole blood viscosity (P<0.01), plasma viscosity (P<0.01) and fibrinogen content (P<0) in rats. .01) also significantly inhibits platelet aggregation in rats. Bazhen Decoction (Group II) also promotes the depolymerization of platelets. Conclusion: A certain dose of Bazhen Decoction can obviously improve the “viscosity”, “concentration”, “condensation”, and “poly” status of blood, and provide preliminary experimental basis for the effect of Bazhen Decoction in promoting blood circulation and removing blood stasis. .
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