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目的总结低级别胶质瘤继发癫的治疗经验。方法回顾性分析46例低级别胶质瘤继发癫病人的临床资料,采用视频脑电图(VEEG)、脑磁图(MEG)定位致灶和功能区,术中联合应用立体定向引导、术中B超、皮质电刺激等技术并配合伽玛刀治疗。结果肿瘤全切除22例,大部切除10例,穿刺活检14例。随访46例,时间13~74个月。复发4例,死亡2例,余病人恢复良好。结论手术联合伽玛刀技术的应用是治疗低级别胶质瘤继发癫的有效方法。
Objective To summarize the experience of treatment of low-grade glioma secondary epilepsy. Methods The clinical data of 46 patients with low-grade glioma secondary to epilepsy were retrospectively analyzed. VEEG and MEG were used to locate the foci and functional areas. Stereotactic guidance , Intraoperative B ultrasound, cortical stimulation and other techniques and gamma knife treatment. Results Totally resected tumor in 22 cases, mostly in 10 cases, 14 cases of biopsy. Follow-up 46 cases, the time of 13 to 74 months. 4 cases of recurrence, 2 cases of death, the rest of the patients recovered well. Conclusion The application of surgery combined with gamma knife technique is an effective method for treating secondary epilepsy in low grade gliomas.