In order to predict the pressure drop, collection efficiency, velocity, temperature and mole fraction of vapor in an industrial venturi scrubber with water spraying for converter gas cooling, a three-dimensional model of heat and mass transfer with phase change is established. The gas flow and liquid droplets are treated as a continuous phase with a Eulerian approach and as a discrete phase with a Lagrangian approach, respectively. The coupled problem of heat, force, and mass transfers between gas flow and liquid droplets is solved by a commercial computational fluid dynamics(CFD) package, FLUENT. The numerical results show that the water injections have an important influence on the distributions of pressure, velocity, temperature, and mole fraction of vapor, especially for the spraying region in the throat. In the spraying region, the pressure drop is higher and the velocity is lower than in other regions due to the gas-droplet drag, while the temperature is lower because the droplet absorbs large amounts of heat from the high temperature gas and the mole fraction of vapor is higher due to the phase change of the liquid droplet. A number of cases with different water-to-gas volume flow ratios and baffle openings were simulated. The dependence of pressure drop, velocity, temperature, mole fraction of vapor, and collection efficiency on both the water-to-gas volume flow ratio and baffle opening are analyzed. The good agreements between simulation results and experiment data of pressure drop, temperature, and collection efficiency validate the model. The model should facilitate optimization of the venturi scrubber design in order to give better performance with lower pressure drops and higher collection efficiency.