A long short-term memory (LSTM) neural net-work has excellent leaing ability applicable to time series of nuclear pulse signals. It can accurately estimate parameters associated with amplitude, time, and so on, in digitally shaped nuclear pulse signals—especially signals from overlapping pulses. By leaing the mapping rela-tionship between Gaussian overlapping pulses after digital shaping and exponential pulses before shaping, the shaping parameters of the overlapping exponential nuclear pulses can be estimated using the LSTM model. Firstly, the Gaussian overlapping nuclear pulse (ONP) parameters which need to be estimated received Gaussian digital shaping treatment, after superposition by multiple expo-nential nuclear pulses. Secondly, a dataset containing multiple samples was produced, each containing a sequence of sample values from Gaussian ONP, after digital shaping, and a set of shaping parameters from exponential pulses before digital shaping. Thirdly, the Training Set in the dataset was used to train the LSTM model. From these datasets, the values sampled from the Gaussian ONP were used as the input data for the LSTM model, and the pulse parameters estimated by the current LSTM model were calculated by forward propagation. Next, the loss function was used to calculate the loss value between the network-estimated pulse parameters and the actual pulse parameters. Then, a gradient-based optimiza-tion algorithm was applied, to feedback the loss value and the gradient of the loss function to the neural network, to update the weight of the LSTM model, thereby achieving the purpose of training the network. Finally, the sampled value of the Gaussian ONP for which the shaping param-eters needed to be estimated was used as the input data for the LSTM model. After this, the LSTM model produced the required nuclear pulse parameter set. In summary, experimental results showed that the proposed method overcame the defect of local convergence encountered in traditional methods and could accurately extract parame-ters from multiple, severely overlapping Gaussian pulses, to achieve optimal estimation of nuclear pulse parameters in the global sense. These results support the conclusion that this is a good method for estimating nuclear pulse parameters.