应用~（９９ｍ）Ｔｃ直接标记还原单克隆抗体的方法，对荷人肺腺癌裸鼠进行放免显像研究。经测定，此方法的标记率为９６％，经免疫组化法及间接免疫荧光法证实，标记后抗体仍保持较好的免疫活性。在荷瘤裸鼠体内的分布实验表明，经尾静脉注射标记抗体１６小时，在肿瘤组织中出现相对较高的特异性浓聚。γ－闪烁图显示出清晰的肿瘤图像。 Using 99mTc direct labeling method to reduce monoclonal antibodies, radioimmunoimaging of nude mice bearing human lung adenocarcinoma was studied. The labeling rate of this method was determined to be 96%. It was confirmed by immunohistochemistry and indirect immunofluorescence that the labeled antibody still maintained good immune activity. The distribution experiments in tumor-bearing nude mice showed that after injection of labeled antibody through the tail vein for 16 hours, relatively high specific concentrations appeared in the tumor tissue. The gamma scintigraphy shows a clear tumor image.