本文采用 β 榄香烯处理小鼠H2 2肝癌亚系HCa F ,提取榄香烯瘤苗可溶性上清作为粗制肿瘤抗原 ,制备抗原冲击(pulsed)的树突状细胞 ,研究其抗瘤作用及机制。结果表明榄香烯瘤苗抗原冲击的树突状细胞可诱导对HCa F瘤株的MHC非限制性免疫应答 ,继承性转输后对HCa F瘤株攻击有免疫保护效应 ;体外可激发脾不粘附细胞活化增殖和加强杀瘤细胞活性。 In this study, β-elemene was used to treat the mouse H2 2 hepatic carcinoma subfamily HCa F, and the soluble supernatant of elemene vaccine was extracted as a crude tumor antigen to prepare pulsed dendritic cells for study of their anti-tumor effect. mechanism. The results showed that the dendritic cells impacted by the elemene tumor vaccine could induce the MHC non-restricted immune response to the HCa F tumor strain. After the inherited transfusion, there was an immunoprotective effect against the HCa F tumor strain challenge; the spleen was not stimulated in vitro. Adherent cells activate proliferation and enhance killer cell activity.