论文部分内容阅读
目的观察初期诊断妊娠高血压综合征(PIHS)患者24-h动态血压变化特点。方法应用动态血压监测仪观察63例初期诊断PIHS患者(PIHS组)和健康孕妇对照(C组)的24-h动态血压,分析昼夜变化特征。PIHS组随访结束时,评定为轻度PIHS者20例(A1组)、中度PIHS者25例(A2组)和重度PIHS者18例(A3组),分层分析血压变异性与其病情的关系。结果 A1、A2和A3组24-h、白天和夜间的收缩压(SBP)、舒张压(DBP)和脉压均高于C组(P<0.05),但A2、A3两组无统计学差异(P>0.05)。PIHS组24-h、白天和夜间的SBP和DBP变异性均较C组高(P<0.05),且随严重程度的增加而增加(P<0.05)。PIHS组24-h、白天及夜间血压负荷均高于C组(P<0.05),且随严重程度的增加而增加(P<0.05)。PIHS组SBP和DBP夜间下降值和下降率均小于C组(P<0.05)。结论 PIHS患者血压变异性与其病情相关。
Objective To observe the changes of 24-h ambulatory blood pressure in patients with pregnancy-induced hypertension (PIHS) during the initial diagnosis. Methods The ambulatory blood pressure of 63 PIH patients (PIHS group) and healthy pregnant women (C group) were observed by ambulatory blood pressure monitor. The 24-hour ambulatory blood pressure was analyzed. At the end of follow-up, 20 patients with mild PIH (group A1), 25 with moderate PIHS (group A2), and 18 with severe PIH (group A3) at the end of the PIHS group were analyzed stratified for the relationship between variability of BPH and their disease . Results The systolic blood pressure (SBP), diastolic blood pressure (DBP) and pulse pressure in groups A1, A2 and A3 were higher than those in group C (P <0.05) at 24h, but no significant difference was found between A2 and A3 (P> 0.05). The changes of SBP and DBP in 24 h at daytime and at night in PIHS group were higher than those in C group (P <0.05), and increased with the severity (P <0.05). The load of 24 h, daytime and nocturnal blood pressure in PIHS group was higher than that in C group (P <0.05), and increased with the severity (P <0.05). The SBP and DBP decrease in nighttime and decrease rate in PIHS group were less than those in C group (P <0.05). Conclusion The variability of blood pressure in patients with PIHS is related to their condition.